Testing for drug allergy
نویسندگان
چکیده
منابع مشابه
Desensitization for drug allergy.
PURPOSE OF REVIEW Desensitization for drug allergy is the induction of temporary clinical unresponsiveness to drug antigens. Gradual reintroduction of small doses of drug antigen at fixed time intervals allows for the delivery of full therapeutic doses, protecting patients from anaphylaxis. Rapid desensitizations permit the use of essential antibiotics in severely infected allergic patients or ...
متن کاملSurvey of Drug Allergy Testing, Challenge, and Desensitization Practice
Background: The lack of standardized skin test products to determine a patient’s (hyper-) sensitivity to medications has required physicians to empirically develop their own testing procedures. These approaches include puncture and intradermal skin tests, patch tests and medication challenges. Desensitization protocols are also frequently used when the necessity of a particular medication is ur...
متن کاملDrug-induced exanthems: correlation of allergy testing with histologic diagnosis.
BACKGROUND Skin biopsies are commonly performed to confirm drug-induced exanthem (DIE). However, the relevance of histologic examination in discriminating between DIE and non-DIE (NDIE) is controversial. OBJECTIVE A retrospective analysis was performed to evaluate the reliability of histologic diagnosis of DIE. METHODS In all, 91 patients with a skin biopsy specimen of an acute exanthem tem...
متن کاملNew allergy drug excipient allergy
Background Because of its rarity, drug excipients allergy is often unsuspected by the doctors. Some times the active drug is blamed and discontinued unnecessarily when the real culprit is drug excipients. This was suspected when patients reported exacerbation of urticaria with anti histaminic which are actually used for treating urticaria. After suspecting drug excipient as the cause of allergy.
متن کاملDrug allergy
Allergic drug reactions occur when a drug, usually a low molecular weight molecule, has the ability to stimulate an immune response. This can be done in one of two ways. The first is by binding covalently to a self-protein, to produce a haptenated molecule that can be processed and presented to the adaptive immune system to induce an immune response. Sometimes the drug itself cannot do this but...
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ژورنال
عنوان ژورنال: Australian Prescriber
سال: 1994
ISSN: 0312-8008,1839-3942
DOI: 10.18773/austprescr.1994.059